Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737769 | 0.87 | LTA4H (0.52) | PPARGPPARACYP19A1KMT2AHPGD | |
| SCHEMBL593272 | 0.84 | CYP19A1 (0.58) | CYP19A1KMT2AHPGDASAH1ELANE | |
| SCHEMBL5478152 | 0.82 | LTA4H (0.55) | PPARGPPARALTA4HSRD5A2ELANE | |
| SCHEMBL6224844 | 0.82 | LTA4H (0.55) | PPARGPPARALTA4HSRD5A2ELANE | |
| Malonic Acid SCHEMBL8752798 | 0.82 | LTA4H (0.49) | PPARGPPARACYP19A1KMT2AHPGD | |
| SCHEMBL27396289 | 0.82 | CYP19A1 (0.56) | CYP19A1KMT2AHPGDELANELMNA | |
| SCHEMBL1931453 | 0.82 | KMT2A (0.54) | CYP19A1KMT2AHPGDELANELMNA | |
| SCHEMBL8060201 | 0.81 | SRD5A2 (0.58) | PPARGPPARACYP19A1LTA4HSRD5A2 | |
| SCHEMBL7564565 | 0.81 | ASAH1 (0.55) | PPARGPPARACYP19A1KMT2AASAH1 | |
| SCHEMBL538524 | 0.80 | CYP19A1 (0.76) | CYP19A1KMT2AHPGDASAH1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10675278-B2 | Crush resistant delayed-release dosage forms | Grünenthal GmbH (DE) | 2020-06-09 | — | — | US | disclosed |
| US-20180369235-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2018-12-27 | — | — | US | disclosed |
| US-20170312271-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9750701-B2 | Pharmaceutical dosage form | Grünenthal GmbH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20160199305-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20160184297-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20160120810-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2016-05-05 | — | — | US | disclosed |
| US-20150374630-A1 | Crush resistant delayed-release dosage forms | GRUENENTHAL GMBH (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20150290138-A1 | Crush resistant delayed-release dosage forms | Grünenthal GmbH (DE) | 2015-10-15 | — | — | US | disclosed |
| US-20140322323-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2014-10-30 | — | — | US | disclosed |
| US-20140322311-A1 | CRUSH RESISTAN DELAYED-RELEASE DOSAGE FORM | Grünenthal GmbH (DE) | 2014-10-30 | — | — | US | disclosed |
| US-20140079780-A1 | Crush resistant delayed-release dosage forms | GRUENENTHAL GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-20130251759-A1 | PHARMACEUTICAL DOSAGE FORM | GRUENENTHAL GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-8383152-B2 | Pharmaceutical dosage form | GRUENENTHAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| EP-2249811-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| US-20100151028-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | GRUNENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20090202634-A1 | PHARMACEUTICAL DOSAGE FORM | GRUNENTHAL GMBH (DE) | 2009-08-13 | — | — | US | disclosed |
| WO-2009092601-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2009-07-30 | — | — | WO | disclosed |
| US-20080311187-A1 | CRUSH RESISTAN DELAYED-RELEASE DOSAGE FORM | GRUNENTHAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
| US-20060193914-A1 | Crush resistant delayed-release dosage forms | ENDO PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |