Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 10/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.40 |
| ▸ | PRKCG | P05129 | 2/20 | 0.40 |
| ▸ | PRKCB | P05771 | 2/20 | 0.40 |
| ▸ | PRKCH | P24723 | 2/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | ABHD16A | O95870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936317 | 1.00 | PRKCA (0.49) | PRKCAPPARGSMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL664887 | 1.00 | PRKCA (0.49) | PRKCAPPARGSMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL5936344 | 1.00 | PRKCA (0.49) | PRKCAPPARGSMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL10186552 | 0.98 | PRKCA (0.51) | PRKCAPPARGPRKD3PRKCGPRKCB | |
| SCHEMBL21182172 | 0.98 | PRKCA (0.51) | PRKCAPPARGPRKD3PRKCGPRKCB | |
| SCHEMBL666234 | 0.98 | PRKCA (0.51) | PRKCAPPARGPRKD3PRKCGPRKCB | |
| SCHEMBL663160 | 0.98 | PRKCA (0.51) | PRKCAPPARGPRKD3PRKCGPRKCB | |
| SCHEMBL664841 | 0.98 | PRKCA (0.51) | PRKCAPPARGPRKD3PRKCGPRKCB | |
| SCHEMBL10186550 | 0.98 | PRKCA (0.51) | PRKCAPPARGPRKD3PRKCGPRKCB | |
| SCHEMBL10186551 | 0.98 | PRKCA (0.51) | PRKCAPPARGPRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060030719-A1 | Cis-3,5-disubstituted-dihydro-furan-2-ones and the preparation and use thereof | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030719-A1 | Cis-3,5-disubstituted-dihydro-furan-2-ones and the preparation and use thereof | CBR3, CYP4F3, DHODH | PRKCA 4171/4885PPARG 3771/4885SMN1; SMN2 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.