Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | GUSB | P08236 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936675 | 0.94 | NR1H4 (0.67) | NR1H4KMT2AMEN1SMPD1NPC1 | |
| SCHEMBL27966079 | 0.85 | NR1H4 (0.71) | NR1H4KMT2AMEN1SMPD1NPC1 | |
| SCHEMBL7078440 | 0.83 | NR1H4 (0.72) | NR1H4KMT2AMEN1SMPD1NPC1 | |
| SCHEMBL5936634 | 0.82 | SMPD1 (0.62) | NR1H4KMT2AMEN1SMPD1RAB9A | |
| SCHEMBL9415806 | 0.81 | NR1H4 (1.00) | NR1H4KMT2AMEN1SMPD1NPC1 | |
| SCHEMBL11550139 | 0.81 | NR1H4 (0.81) | NR1H4KMT2AMEN1SMPD1NPC1 | |
| SCHEMBL7076430 | 0.81 | KMT2A (0.65) | NR1H4KMT2AMEN1SMPD1NPC1 | |
| SCHEMBL15838871 | 0.78 | SMPD1 (0.77) | NR1H4KMT2AMEN1SMPD1NPC1 | |
| SCHEMBL7410475 | 0.78 | SMPD1 (0.78) | NR1H4KMT2AMEN1SMPD1NPC1 | |
| SCHEMBL1608032 | 0.78 | SMPD1 (1.00) | NR1H4KMT2AMEN1SMPD1GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | NR1H4 160/4885KMT2A 1515/4885MEN1 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.