SCHEMBL59378

SCHEMBL59378

C1=C(C2(C3CCCCC3)CCCCC2)CCCC1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP19A1 P11511 6/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27699094 0.92 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3CYP19A1
SCHEMBL16163535 0.92 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3CYP19A1
SCHEMBL9821528 0.89 CYP19A1 (0.31) CYP19A1
SCHEMBL8362305 0.86 MEN1 (0.33) MEN1KMT2ACYP19A1
SCHEMBL11203592 0.80 CYP19A1 (0.32) MEN1KMT2ACYP19A1
SCHEMBL8366209 0.80 CYP19A1 (0.33) CYP19A1
SCHEMBL8632181 0.77
SCHEMBL11458345 0.75 CYP19A1 (0.31) MEN1KMT2ACYP19A1
SCHEMBL11458346 0.74
SCHEMBL7488337 0.71 CHRM3 (0.33) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 802 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 US claimed
US-20230203378-A1 FORMULATIONS OF BIOREACHABLE DOPANTS FOR LIQUID CRYSTALS KENT STATE UNIVERSITY 2023-06-29 US claimed
US-20220025267-A1 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS ZYMERGEN ACQUISITION SUB, INC. 2022-01-27 US claimed
EP-3891252-A2 BIOREACHABLE CHIRAL DOPANTS FOR LIQUID CRYSTAL APPLICATIONS Zymergen Inc. (US) 2021-10-13 EP claimed
US-6602562-B2 High dielectric anisotropy and clearing point with little impact on voltage holding ratio, low temperature stability and response time MERCK PATENT GESELLSCHAFT MIT (DE) 2003-08-05 US claimed
US-20030113482-A1 Realignment layer; field has a component parallel to the liquid-crystal layer; positive dielectric anisotropy MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-06-19 US claimed
US-6217792-B1 Chiral dopants MERCK PATENT GMBH (DE) 2001-04-17 US claimed
EP-0408995-B1 Liquid crystal medium with limited temperature-dependence of the d/p coefficient MERCK PATENT GMBH (DE) 1995-11-08 EP claimed
US-5139698-A Achiral liquid crystal compound with doping component MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1992-08-18 US claimed
US-11814563-B2 Bioreachable chiral dopants for liquid crystal applications ZYMERGEN INC. (US) 2023-11-14 US disclosed
US-20230203378-A1 FORMULATIONS OF BIOREACHABLE DOPANTS FOR LIQUID CRYSTALS KENT STATE UNIVERSITY 2023-06-29 US disclosed
US-11667841-B2 Dibenzofuran and dibenzothiophene derivatives MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
CN-109627658-B Composition comprising functionalized polyvinyl alcohol and nanocapsules containing a liquid crystalline medium 默克专利股份有限公司 2023-02-17 CN disclosed
EP-3638657-B1 DIBENZOFURAN DERIVATIVES AND DIBENZOTHIOPHENE DERIVATIVES MERCK PATENT GMBH (DE) 2022-07-20 EP disclosed
WO-1989008649-A1 HETEROCYCLIC 1,2-DIFLUOROBENZENE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
WO-1989008632-A1 DERIVATIVES OF 2,3-DIFLUOROPHENOL MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
WO-1989008689-A1 2,3-DIFLUOROBENZENE DERIVATIVES AND THEIR USE AS COMPONENTS OF LIQUID CRYSTAL MEDIA MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
WO-1989008633-A1 DIFLUOROBENZOL DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
EP-0332007-A1 Derivatives of 2,3-difluorohydroquinone MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed
EP-0332024-A1 Heterocyclic derivatives of 1,2-difluorobenzene MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667841-B2 Dibenzofuran and dibenzothiophene derivatives DDT, MYT1, DBF4 SLC6A2 2126/4885SLC6A4 2503/4885SLC6A3 917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.