⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790112 | 0.76 | RECQL (0.32) | — | |
| SCHEMBL5057275 | 0.76 | TSHR (0.53) | — | |
| SCHEMBL28604834 | 0.74 | RECQL (0.31) | — | |
| SCHEMBL15868130 | 0.72 | CA1 (0.33) | — | |
| SCHEMBL19154262 | 0.72 | CA1 (0.32) | — | |
| SCHEMBL3096305 | 0.72 | — | — | |
| SCHEMBL329520 | 0.72 | — | — | |
| SCHEMBL28552161 | 0.71 | — | — | |
| SCHEMBL11647729 | 0.71 | HCAR2 (0.39) | — | |
| SCHEMBL11698106 | 0.71 | HCAR2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078159-A1 | NOVEL PD1-TARGETED IL-15 IMMUNOCYTOKINE and VITOKINE FUSIONS | CUGENE INC (US) | 2026-03-19 | — | — | US | disclosed |
| US-20250255938-A1 | CHOLIX TOXIN-DERIVED FUSION MOLECULES FOR ORAL DELIVERY OF BIOLOGICALLY ACTIVE CARGO | THORNHILL THERAPEUTICS INC (US) | 2025-08-14 | — | — | US | disclosed |
| US-20250242039-A1 | TOXIN-DERIVED DELIVERY CONSTRUCTS | THORNHILL THERAPEUTICS INC (US) | 2025-07-31 | — | — | US | disclosed |
| EP-4583901-A1 | NOVEL PD1-TARGETED IL-15 IMMUNOCYTOKINE AND VITOKINE FUSIONS | Cugene Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| EP-4584379-A1 | NOVEL PD1-TARGETED IL-2 IMMUNOCYTOKINE AND VITOKINE FUSIONS | Cugene Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-120152731-A | Novel PD 1-targeted IL-15 immunocytokines and VitoKine fusions | 科优基因公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120153079-A | Novel PD 1-targeted IL-2 immunocytokines and VitoKine fusions | 科优基因公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-115087464-B | Novel interleukin-15 (IL-15) fusion proteins and uses thereof | 科优基因公司 | 2025-02-25 | — | — | CN | disclosed |
| EP-4461750-A2 | NOVEL INTERLEUKIN-15 (IL-15) FUSION PROTEINS AND USES THEREOF | Cugene Inc. (US) | 2024-11-13 | — | — | EP | disclosed |
| US-20240299565-A1 | TOXIN-DERIVED DELIVERY CONSTRUCTS | APPLIED MOLECULAR TRANSPORT INC. | 2024-09-12 | — | — | US | disclosed |
| US-20060205037-A1 | Modified transferrin fusion proteins | BIOREXIS PHARMACEUTICAL CORPORATION | 2006-09-14 | — | — | US | disclosed |
| EP-1611093-A4 | MODIFIED TRANSFERRIN FUSION PROTEINS | BIOREXIS PHARMACEUTICAL CORP (US) | 2006-06-28 | — | — | EP | disclosed |
| EP-1663278-A2 | EPO MIMETIC PEPTIDES AND FUSION PROTEINS | Biorexis Pharmaceutical Corporation (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2006049983-A2 | PEPTIDE YY MODIFIED TRANSFERRIN FUSION PROTEINS | BIOREXIS PHARMACEUTICAL CORPORATION (US) | 2006-05-11 | — | — | WO | disclosed |
| EP-1611093-A2 | MODIFIED TRANSFERRIN FUSION PROTEINS | Biorexis Pharmaceutical Corporation (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2005021579-A2 | EPO MIMETIC PEPTIDES AND FUSION PROTEINS | BIOREXIS PHARMACEUTICAL CORPORATION (US) | 2005-03-10 | — | — | WO | disclosed |
| WO-2004020405-A2 | MODIFIED TRANSFERRIN FUSION PROTEINS | BIOREXIS PHARMACEUTICAL CORPORATION (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004019872-A2 | ORAL DELIVERY OF MODIFIED TRANSFERRIN FUSION PROTEINS | BIOREXIS PHARMACEUTICAL CORPORATION (US) | 2004-03-11 | — | — | WO | disclosed |
| US-6616944-B2 | Active agent and polyol ester having biodegradable hydroxy carboxylic ester groups attached to backbone | MEDINNOVA GESELLSCHAFT FUR MEDIZINSCHE INNOVATIONEN AUS ADKADEMISCHER FORSCHUNG MBH (DE) | 2003-09-09 | — | — | US | disclosed |
| US-20010047074-A1 | Self-assembling colloidal carriers for protein delivery | NANOHALE MANAGEMENT LTD. (DE) | 2001-11-29 | — | — | US | disclosed |