Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 13/20 | 1.00 |
| ▸ | GRIK2 | Q13002 | 13/20 | 1.00 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.57 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15312401 | 1.00 | GRIK1 (1.00) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL7751545 | 1.00 | GRIK1 (1.00) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL594101 | 1.00 | GRIK1 (1.00) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL9087042 | 0.98 | GRIK1 (0.96) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL9087046 | 0.98 | GRIK1 (0.96) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL6050002 | 0.87 | GRIK1 (0.75) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL9647546 | 0.83 | SLC1A1 (0.77) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL23834363 | 0.82 | GRIK1 (0.69) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| SCHEMBL23834361 | 0.82 | GRIK1 (0.69) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL23834395 | 0.81 | GRIK1 (0.67) | GRIK1GRIK2SLC1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629911-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150224193-A1 | PHOTOREACTIVE REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-08-13 | — | — | US | disclosed |
| US-9097707-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130137113-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-30 | — | — | US | disclosed |
| US-8309350-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120190094-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-07-26 | — | — | US | disclosed |
| US-8114843-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-14 | — | — | US | disclosed |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150224193-A1 | PHOTOREACTIVE REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | PPP1R10, PPP6R3, ANKRD52 | GRIK1 3703/4885GRIK2 3511/4885SLC1A1 3460/4885 |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | PPP1R10, PPP6R3, ANKRD52 | GRIK1 3703/4885GRIK2 3511/4885SLC1A1 3460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.