PPP6R3 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

	Compound	Confidence	Supporting neighbours

Clinical trials — most relevant to PPP6R3 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Rectal Tacrolimus in the Treatment of Resistant Ulcerative Proctitis	PHASE4	COMPLETED
The G Protein-Coupled Receptor Kinase Type 2 Inhibitor Paroxetine as Adjunctive Therapy to Improve Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus	PHASE3	UNKNOWN
A Multicenter Study of NAP (AL-108) in Schizophrenia	PHASE2	COMPLETED
Everolimus in Treating Patients With Relapsed or Refractory Multiple Myeloma	PHASE2	COMPLETED
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients	PHASE2	COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL	PHASE1/PHASE2	RECRUITING
Everolimus for Children With Recurrent or Progressive Ependymoma	PHASE2	COMPLETED
Lapatinib Ditosylate in Treating Patients With Unresectable Liver or Biliary Tract Cancer	PHASE2	COMPLETED
Evaluating MED2005 & Nitrostat Bioavailability	PHASE1	COMPLETED
Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma	PHASE1	COMPLETED
PS-341 and Radiation to Treat Advanced Cancer of the Head and Neck	PHASE1	COMPLETED
Phase I Dose Finding and Proof-of-concept Study of Panobinostat With Standard Dose Cytarabine and Daunorubicin for Untreated Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome	PHASE1	COMPLETED
Safety Study of Infusion of SGT-53 to Treat Solid Tumors	PHASE1	COMPLETED
Novel Molecular Targets and Innovative Therapeutic Perspective in Medulloblastoma	EARLY_PHASE1	RECRUITING
Quantification of GADD34 Expression in RA	nan	COMPLETED
Immune Signature of Palmoplantar Pustulosis	nan	COMPLETED
NGS in Gallbladder Cancer and Response to Treatment	nan	RECRUITING
Autophagy in Systemic Lupus Erythematosus	nan	UNKNOWN
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases	nan	NOT_YET_RECRUITING
Recombinant Interferon Alfa-2b in Treating Patients With Melanoma	nan	COMPLETED
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population	nan	COMPLETED
Lymphoid Tyrosine Phosphatase Gene Polymorphisms in Inflammatory Bowel Disease	nan	UNKNOWN
Studying Phosphorus Metabolism	nan	COMPLETED
Protein Synthesis in the Brain of Patients With Fragile X Syndrome	nan	COMPLETED
IVF Outcome in Polycystic Ovary Syndrome Patients	nan	UNKNOWN
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH)	nan	COMPLETED
miRNA as a Growth Plate Marker After GH	nan	UNKNOWN
Genes, Proteins, and Metabolites in Drug-resistant Epilepsy (DRE) Patients	nan	NOT_YET_RECRUITING
Abnormalities in the Effects of Insulin and Exercise on Glucose- and Lipid Metabolism in Obesity and Type 2 Diabetes	nan	COMPLETED
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a PPP6R3 binder may also engage these)

Protein	Name	Similarity
Q922D4	—	1.000	Q922D4 →
Q5F471	—	1.000	Q5F471 →
Q6NRF1	—	1.000	Q6NRF1 →
Q6NRI0	—	0.997	Q6NRI0 →
Q9LYZ7	—	0.994	Q9LYZ7 →
Q8R3Q2	—	0.991	Q8R3Q2 →
Q8H0T4	—	0.991	Q8H0T4 →
PPP6R1	Serine/threonine-protein phosphatase 6 regulatory subunit 1	0.990	landscape →
Q7TSI3	—	0.989	Q7TSI3 →
Q19317	—	0.989	Q19317 →
A5HEI1	—	0.989	A5HEI1 →
Q8GY23	—	0.989	Q8GY23 →
Q75E32	—	0.989	Q75E32 →
O75170	—	0.989	O75170 →
Q5ICL9	—	0.988	Q5ICL9 →
Q7Z3E5	—	0.988	Q7Z3E5 →
Q5XG71	—	0.988	Q5XG71 →
Q5PQS3	—	0.988	Q5PQS3 →
Q8BH53	—	0.988	Q8BH53 →
Q5JWR5	—	0.987	Q5JWR5 →
Q14D04	—	0.987	Q14D04 →
Q9DDT2	—	0.987	Q9DDT2 →
G5EFD2	—	0.987	G5EFD2 →
A6QP06	—	0.987	A6QP06 →
Q92539	—	0.987	Q92539 →
A7YDW0	—	0.987	A7YDW0 →
Q6ZPS6	—	0.987	Q6ZPS6 →
BPTF	Nucleosome-remodeling factor subunit BPTF	0.987	landscape →
B0CM26	—	0.987	B0CM26 →
Q0VF22	—	0.987	Q0VF22 →