Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.91 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27752275 | 1.00 | TSHR (0.91) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| Adipic Acid SCHEMBL2852301 | 1.00 | TSHR (0.91) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| SCHEMBL29242700 | 0.98 | TSHR (0.95) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| Glutarate SCHEMBL28741985 | 0.98 | TSHR (0.95) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| Adipic Acid SCHEMBL3799583 | 0.98 | TSHR (0.95) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| SCHEMBL10792676 | 0.95 | TSHR (0.91) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| SCHEMBL194401 | 0.95 | TSHR (0.90) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| Glutarate SCHEMBL21253151 | 0.95 | TSHR (1.00) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| Glutarate SCHEMBL6415495 | 0.95 | TSHR (1.00) | TSHRLMNASLC22A6ALDH1A1NFKB1 | |
| Adipic Acid SCHEMBL6408549 | 0.95 | TSHR (0.90) | TSHRLMNASLC22A6ALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060194711-A1 | Preformulated additive for a composition for treating textile fiber articles and use of said additive as care agent | PROCTER & GAMBLE COMPAMY, THE | 2006-08-31 | — | — | US | disclosed |
| US-20030050218-A1 | Preformulated additive for a composition for treating textile fiber articles and use of said additive as care agent | PROCTER & GAMBLE COMPAMY, THE | 2003-03-13 | — | — | US | disclosed |
| US-6528473-B1 | Nanostructured particles comprising detergents, biocides, optical brightners or bleaches encapsulated in homo and/or copolymer matrices used for cleaning surfaces or laundering clothing | RHODIA CHIMIE (FR) | 2003-03-04 | — | — | US | disclosed |