Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5082902 | 0.89 | LMNA (0.41) | TSHRTP53LMNAMEN1KMT2A | |
| SCHEMBL5941435 | 0.85 | TSHR (0.49) | TSHRTP53LMNAMEN1KMT2A | |
| SCHEMBL5941274 | 0.82 | MEN1 (0.47) | TSHRTP53LMNAMEN1KMT2A | |
| SCHEMBL5186628 | 0.81 | SLC1A3 (0.45) | TSHRTP53LMNAMEN1KMT2A | |
| SCHEMBL5941277 | 0.81 | TSHR (0.47) | TSHRTP53LMNACYP2C19MEN1 | |
| SCHEMBL1072082 | 0.80 | LMNA (0.39) | TSHRTP53LMNACYP2C19MEN1 | |
| SCHEMBL5941243 | 0.79 | TSHR (0.49) | TSHRTP53LMNAMEN1KMT2A | |
| SCHEMBL1786404 | 0.78 | LMNA (0.51) | TSHRTP53LMNAMEN1KMT2A | |
| SCHEMBL5082873 | 0.78 | MEN1 (0.43) | TSHRTP53LMNAMEN1KMT2A | |
| SCHEMBL1784284 | 0.77 | LMNA (0.50) | TSHRTP53LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060287446-A1 | Catalyst component for olefin polymerization and catalyst comprising the same | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CHINA PETROLEUM & CHEMICAL COPORATION (CN) | 2006-12-21 | — | — | US | disclosed |