⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932133 | 0.79 | — | — | |
| SCHEMBL9395635 | 0.78 | GABRR1 (0.44) | — | |
| SCHEMBL11041667 | 0.76 | ACE (0.36) | — | |
| SCHEMBL6028612 | 0.73 | — | — | |
| SCHEMBL7198148 | 0.73 | — | — | |
| SCHEMBL16853135 | 0.73 | GABRR1 (0.58) | — | |
| SCHEMBL2179702 | 0.73 | — | — | |
| SCHEMBL9227938 | 0.73 | — | — | |
| SCHEMBL1226620 | 0.71 | — | — | |
| SCHEMBL6976745 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240042015-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. | 2024-02-08 | — | — | US | disclosed |
| CN-116322788-A | Cyclic RNA compositions and methods | 奥纳治疗公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116034114-A | Cyclic RNA compositions and methods | 奥纳治疗公司 | 2023-04-28 | — | — | CN | disclosed |
| EP-4153244-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | Orna Therapeutics, Inc. (US) | 2023-03-29 | — | — | EP | disclosed |
| EP-4121453-A2 | CIRCULAR RNA COMPOSITIONS AND METHODS | Orna Therapeutics, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021236855-A1 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021189059-A2 | CIRCULAR RNA COMPOSITIONS AND METHODS | ORNA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| US-20060121019-A1 | Compositions for treating cystic fibrosis | BUDNY JOHN A | 2006-06-08 | — | — | US | disclosed |
| US-20050158253-A1 | Enzyme and an enzyme-anchor complex; degrades biofilm structures; complex acts as a bactericide | PHARMACAL BIOTECHNOLOGIES, LLC. | 2005-07-21 | — | — | US | disclosed |
| US-6830745-B1 | Compositions for treating biofilm | PHARMACAL BIOTECHNOLOGIES, LLC | 2004-12-14 | — | — | US | disclosed |
| US-20020037260-A1 | Compositions for treating biofilm | BUDNY JOHN A (US) | 2002-03-28 | — | — | US | disclosed |
| US-20020022005-A1 | Compositions for treating cystic fibrosis | ALLOTROPE PHARMACEUTICALS, INC. | 2002-02-21 | — | — | US | disclosed |
| WO-2001093875-A1 | COMPOSITIONS FOR TREATING BIOFILM | PHARMACAL BIOTECHNOLOGIES, LLC (US) | 2001-12-13 | — | — | WO | disclosed |
| WO-1996015449-A1 | DETECTION OF PROCOAGULANT PLATELET-DERIVED MICROPARTICLES IN WHOLE BLOOD | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-05-23 | — | — | WO | disclosed |