Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 0.71 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 5/20 | 0.51 |
| ▸ | CA2 | P00918 | 5/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA11 | O75493 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 4/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | WNT1 | P04628 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TTK | P33981 | 2/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | MARK3 | P27448 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4524087 | 0.83 | CDK2 (1.00) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL29843032 | 0.83 | CDK2 (1.00) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL4520668 | 0.83 | FLT3 (0.55) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL5945808 | 0.83 | FLT3 (0.70) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL5945641 | 0.80 | FLT3 (0.48) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL6534005 | 0.79 | CSNK2A1 (0.48) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL5945662 | 0.79 | CSNK2A1 (0.76) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL5945648 | 0.76 | FLT3 (0.50) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL6221286 | 0.76 | CDK2 (0.65) | CDK2CSNK2A1FLT3CCNA2CCNA1 | |
| SCHEMBL5945670 | 0.75 | DYRK1A (0.65) | CDK2FLT3CCNA2CCNA1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | ASTEX TECHNOLOGY, INC. (GB) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | CCNC, CDK1, CDK7 | CDK2 5/4885CSNK2A1 84/4885CA1 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.