Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.84 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5945883 | 1.00 | HTR1A (0.84) | HTR1ADRD2DRD3 | |
| SCHEMBL5945879 | 1.00 | HTR1A (0.84) | HTR1ADRD2DRD3 | |
| SCHEMBL7881727 | 0.89 | HTR1A (0.66) | HTR1A | |
| SCHEMBL20874538 | 0.89 | HTR1A (0.66) | HTR1A | |
| SCHEMBL20874536 | 0.89 | HTR1A (0.66) | HTR1A | |
| SCHEMBL1544813 | 0.87 | HTR1A (0.64) | HTR1A | |
| SCHEMBL1544811 | 0.87 | HTR1A (0.64) | HTR1A | |
| SCHEMBL1545512 | 0.87 | HTR1A (0.64) | HTR1A | |
| SCHEMBL8168469 | 0.81 | HTR1A (0.58) | HTR1A | |
| SCHEMBL8172160 | 0.81 | HTR1A (0.58) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060217394-A1 | Treatment of anhedonia | SILVAN S. TOMKINS INSTITUTE, INC. | 2006-09-28 | — | — | US | disclosed |
| WO-2006091725-A1 | TREATMENT OF ANHEDONIA | THE SILVAN S. TOMKINS INSTITUTE (US) | 2006-08-31 | — | — | WO | disclosed |