Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5949210 | 0.98 | TSHR (0.37) | TSHRDNM1FAAHTRPV1THRB | |
| SCHEMBL5948858 | 0.91 | TSHR (0.36) | TSHR | |
| SCHEMBL13504740 | 0.90 | DNM1 (0.40) | TSHRDNM1 | |
| SCHEMBL4344245 | 0.81 | DNM1 (0.46) | TSHRDNM1FAAHTRPV1THRB | |
| SCHEMBL11852536 | 0.81 | DNM1 (0.46) | TSHRDNM1FAAHTRPV1THRB | |
| SCHEMBL5948516 | 0.81 | DNM1 (0.46) | TSHRDNM1FAAHTRPV1THRB | |
| SCHEMBL5948727 | 0.79 | TSHR (0.42) | TSHRDNM1FAAHTRPV1THRB | |
| SCHEMBL5948846 | 0.78 | DNM1 (0.42) | TSHRDNM1FAAHTRPV1THRB | |
| SCHEMBL25174145 | 0.74 | TSHR (0.58) | TSHRDNM1FAAHTRPV1THRB | |
| SCHEMBL25171005 | 0.74 | TSHR (0.58) | TSHRDNM1FAAHTRPV1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7101940-B2 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2006-09-05 | — | — | US | disclosed |
| US-7034173-B2 | Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins | BASELL POLYOLEFINE GMBH (DE) | 2006-04-25 | — | — | US | disclosed |
| US-6953829-B2 | Catalyst system and the use thereof | BASELL POLYOLEFINE GMBH (DE) | 2005-10-11 | — | — | US | disclosed |
| US-20030144434-A1 | Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins | EQUISTAR CHEMICALS, LP | 2003-07-31 | — | — | US | disclosed |
| US-20030013913-A1 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | EQUISTAR CHEMICALS, LP | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144434-A1 | Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins | CBR1, COX6C, CBR3 | TSHR 2182/4885DNM1 4094/4885FAAH 1250/4885 |
| US-20030013913-A1 | Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins | SCO2, CNOT1, CYC1 | TSHR 3975/4885DNM1 2698/4885FAAH 3959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.