Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.50 |
| ▸ | NQO2 | P16083 | 6/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15477961 | 1.00 | ESR1 (0.65) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL3827456 | 0.90 | PTGS1 (0.59) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL3827453 | 0.90 | PTGS1 (0.59) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL3827458 | 0.90 | PTGS1 (0.59) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL5954016 | 0.90 | ESR1 (0.53) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL6051034 | 0.90 | ESR1 (0.53) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL5954020 | 0.90 | ESR1 (0.53) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL6051036 | 0.90 | ESR1 (0.53) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL9789510 | 0.87 | NQO2 (0.65) | ESR1ESR2PTGS1PTGS2NQO2 | |
| SCHEMBL9789516 | 0.87 | NQO2 (0.65) | ESR1ESR2PTGS1PTGS2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120115918-A1 | Anti-Viral Compounds | ABBOTT LABORATORIES (US) | 2012-05-10 | — | — | US | disclosed |
| US-4196229-A | NITRILES, ESTERS, AMIDES, SULFONES, AND KETONES | SANDOZ LTD. (CH) | 1980-04-01 | — | — | US | disclosed |
| US-4108887-A | Divinyl stilbenes as optical brighteners | SANDOZ LTD. (CH) | 1978-08-22 | — | — | US | disclosed |
| US-3947471-A | CHROMOGENIC | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115918-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | ESR1 3784/4885ESR2 2700/4885PTGS1 1687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.