SCHEMBL5951499

SCHEMBL5951499

CCC1c2cc(O)ccc2-c2ccc(O)cc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.60
ESR2 Q92731 9/20 0.60
DYRK1A Q13627 1/20 0.56
MEN1 O00255 2/20 0.46
GLA P06280 2/20 0.46
KMT2A Q03164 2/20 0.46
GAA P10253 1/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
NR1I2 O75469 1/20 0.46
GMNN O75496 1/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 1/20 0.46
HSP90AA1 P07900 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6905793 0.78 ESR1 (0.44) ESR1ESR2DYRK1AMEN1GLA
SCHEMBL13303151 0.76 DYRK1A (0.44) ESR1ESR2DYRK1AALDH1A1LMNA
SCHEMBL1658268 0.75 DYRK1A (0.62) ESR1ESR2DYRK1AMEN1GLA
SCHEMBL29742702 0.75 DYRK1A (0.62) ESR1ESR2DYRK1AMEN1GLA
SCHEMBL30633075 0.74 HTR2B (0.40) ESR1ESR2NPC1ALDH1A1LMNA
SCHEMBL12336639 0.74 ESR1 (0.37) ESR1ESR2DYRK1AMEN1GLA
SCHEMBL3977180 0.74 PGR (0.38) ESR1ESR2MEN1KMT2ANPC1
SCHEMBL4790859 0.74 DYRK1A (0.50) ESR1ESR2DYRK1AMEN1GLA
SCHEMBL11384034 0.72 CYP1A2 (0.46) ESR1ESR2MEN1KMT2AALDH1A1
SCHEMBL26774727 0.72 ESR2 (0.49) ESR1ESR2DYRK1AMEN1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7588806-B2 Homeotropically aligned liquid crystal film and process for producing the same CHISSO CORPORATION (JP) 2009-09-15 US disclosed
US-20070073034-A1 Pseudo-donor-containing second-order nonlinear optical chromophores with improved stability and electro-optic polymers covalently incorporating the same PACIFIC WAVE INDUSTRIES, INC. 2007-03-29 US disclosed
US-7101595-B2 Photo-curable fluorene derivative and composition containing the same CHISSO CORPORATION (JP) 2006-09-05 US disclosed
US-20050031801-A1 Photo-curable fluorene derivative and composition containing the same JNC PETROCHEMICAL CORPORATION (JP) 2005-02-10 US disclosed