Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5889674 | 0.82 | HTR2A (0.31) | HTR2CHTR2A | |
| SCHEMBL5952440 | 0.81 | ENPP1 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL5952659 | 0.81 | — | — | |
| SCHEMBL5952361 | 0.80 | PTPN5 (0.32) | — | |
| SCHEMBL5951591 | 0.79 | ENPP1 (0.32) | — | |
| SCHEMBL5951070 | 0.79 | ENPP1 (0.38) | — | |
| SCHEMBL5952656 | 0.78 | — | — | |
| SCHEMBL5952259 | 0.78 | HTR1A (0.35) | — | |
| SCHEMBL5952724 | 0.78 | ENPP1 (0.32) | — | |
| SCHEMBL5953120 | 0.78 | HTR1A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |