Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721700 | 0.80 | — | — | |
| SCHEMBL312355 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2MEN1KMT2ATSHR | |
| Perfluorotoluene SCHEMBL308464 | 0.73 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ATSHR | |
| Perfluorotoluene SCHEMBL28273865 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2ATSHR | |
| Perfluorotoluene SCHEMBL28760715 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL3168128 | 0.70 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL1998599 | 0.69 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL19103513 | 0.69 | SMN1; SMN2 (0.35) | SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL169940 | 0.69 | SMN1; SMN2 (0.35) | SMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL24254677 | 0.67 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | SMN1; SMN2 3518/4885MEN1 718/4885KMT2A 3372/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | SMN1; SMN2 3389/4885MEN1 614/4885KMT2A 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.