Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437404 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL1031712 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL12060779 | 0.74 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL12060766 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL1027879 | 0.71 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL7565478 | 0.70 | ALDH1A1 (0.74) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL5672791 | 0.70 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL15018955 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL14627911 | 0.69 | KMT2A (0.47) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL12060816 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7125475-B2 | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORPORATION (US) | 2006-10-24 | — | — | US | claimed |