Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28218451 | 0.94 | HTR2A (0.45) | HTR2ACYP4A11CYP4F2CA2ALDH1A1 | |
| SCHEMBL27580373 | 0.86 | TDP1 (0.50) | HTR2ACYP4A11CYP4F2CA2ALDH1A1 | |
| SCHEMBL28449485 | 0.82 | HTR2A (0.56) | HTR2ACA2ALDH1A1ESR1ADRA2A | |
| SCHEMBL22463131 | 0.81 | ESR1 (0.44) | HTR2ACYP4A11CYP4F2CA2ALDH1A1 | |
| SCHEMBL8100328 | 0.81 | MAOB (0.59) | HTR2AALDH1A1HSD17B10KDM4ECYP3A4 | |
| 1,4-Butanediol SCHEMBL11501486 | 0.80 | ESR1 (0.54) | ALDH1A1ESR1ADORA3SLC6A2SLC6A3 | |
| SCHEMBL22918238 | 0.80 | CYP4A11 (0.49) | CYP4A11CYP4F2CA2ALDH1A1ESR1 | |
| SCHEMBL8100397 | 0.79 | MAOB (0.57) | HTR2AALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL8087537 | 0.79 | MAOB (0.57) | HTR2AALDH1A1ESR1ADRA2AADORA3 | |
| SCHEMBL8095768 | 0.79 | MAOB (0.57) | HTR2AALDH1A1ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122613-B1 | Method for the production of polycarbonates | GENERAL ELECTRIC COMPANY (US) | 2006-10-17 | — | — | US | claimed |