Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 17/20 | 0.46 |
| ▸ | PPARD | Q03181 | 17/20 | 0.46 |
| ▸ | PPARA | Q07869 | 17/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367383 | 0.95 | GRM2 (0.55) | GRM2PPARGPPARDPPARANR1H2 | |
| SCHEMBL5954097 | 0.90 | GRM2 (0.56) | GRM2PPARGPPARDPPARANR1H2 | |
| SCHEMBL5953747 | 0.86 | GRM2 (0.59) | GRM2PPARGPPARDPPARANR1H2 | |
| SCHEMBL6368217 | 0.86 | GRM2 (0.59) | GRM2PPARGPPARDPPARANR1H2 | |
| SCHEMBL6374660 | 0.86 | GRM2 (0.50) | GRM2PPARGPPARDPPARA | |
| SCHEMBL5953420 | 0.84 | GRM2 (0.56) | GRM2PPARGPPARDPPARANR1H2 | |
| SCHEMBL5807237 | 0.80 | GRM2 (0.56) | GRM2PPARGPPARDPPARANR1H2 | |
| SCHEMBL5953445 | 0.80 | GRM2 (0.56) | GRM2PPARGPPARDPPARANR1H2 | |
| SCHEMBL5953799 | 0.79 | NR1H3 (0.65) | PPARGPPARDPPARANR1H2NR1H3 | |
| SCHEMBL5204898 | 0.78 | PPARA (0.61) | GRM2PPARGPPARDPPARANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060020036-A1 | Methods and compositions to promote bone homestasis | GALAPAGOS N.V. (BE) | 2006-01-26 | — | — | US | disclosed |