Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 16/20 | 0.46 |
| ▸ | PPARG | P37231 | 16/20 | 0.46 |
| ▸ | PPARD | Q03181 | 16/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954101 | 0.89 | GRM2 (0.54) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL5953747 | 0.86 | GRM2 (0.59) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL5807237 | 0.84 | GRM2 (0.56) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL6368217 | 0.82 | GRM2 (0.59) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL5953420 | 0.80 | GRM2 (0.56) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL5954097 | 0.80 | GRM2 (0.56) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL6100087 | 0.80 | GRM2 (0.63) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL5953437 | 0.80 | GRM2 (0.54) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL6175566 | 0.79 | GRM2 (0.60) | GRM2PPARAPPARGPPARDNR1H2 | |
| SCHEMBL6367383 | 0.79 | GRM2 (0.55) | GRM2PPARAPPARGPPARDNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060020036-A1 | Methods and compositions to promote bone homestasis | GALAPAGOS N.V. (BE) | 2006-01-26 | — | — | US | disclosed |