Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420811 | 1.00 | ESR1 (0.67) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL10791730 | 1.00 | ESR1 (0.67) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL31287152 | 0.93 | ESR1 (0.62) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL3305228 | 0.93 | ESR1 (0.62) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL68775 | 0.93 | ESR1 (0.62) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL29802280 | 0.93 | ESR1 (0.62) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL10788082 | 0.87 | ESR1 (0.56) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL5524287 | 0.84 | ESR1 (0.74) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL21404105 | 0.84 | ESR1 (0.54) | ESR1ESR2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL10777847 | 0.82 | ESR2 (1.00) | ESR1ESR2ALDH1A1L3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109274-B2 | Polyarylate compositions | GENERAL ELECTRIC COMPANY (US) | 2006-09-19 | — | — | US | claimed |