SCHEMBL68775

SCHEMBL68775

Oc1ccc(C2(c3ccc(O)c(Cl)c3)CCCCC2)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.62
ESR2 Q92731 4/20 0.62
ACHE P22303 1/20 0.44
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SLC6A4 P31645 8/20 0.42
SLC6A3 Q01959 8/20 0.42
SLC6A2 P23975 6/20 0.42
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
PDE7A Q13946 1/20 0.40
ALOX12 P18054 1/20 0.39
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31287152 1.00 ESR1 (0.62) ESR1ESR2ACHEALDH1A1L3MBTL1
SCHEMBL3305228 1.00 ESR1 (0.62) ESR1ESR2ACHEALDH1A1L3MBTL1
SCHEMBL29802280 1.00 ESR1 (0.62) ESR1ESR2ACHEALDH1A1L3MBTL1
SCHEMBL10791730 0.93 ESR1 (0.67) ESR1ESR2ACHEALDH1A1L3MBTL1
SCHEMBL5953595 0.93 ESR1 (0.67) ESR1ESR2ACHEALDH1A1L3MBTL1
SCHEMBL10788082 0.93 ESR1 (0.56) ESR1ESR2ACHEALDH1A1L3MBTL1
SCHEMBL11420811 0.93 ESR1 (0.67) ESR1ESR2ACHEALDH1A1L3MBTL1
SCHEMBL11320311 0.85 ESR1 (0.47) ESR1ESR2ACHETSHRHSD17B10
SCHEMBL15308146 0.83 ESR1 (0.46) ESR1ESR2ACHEALDH1A1L3MBTL1
SCHEMBL4743330 0.82 ESR1 (0.69) ESR1ESR2ACHEALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1560871-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-08-10 EP claimed
WO-2004041907-A1 METHOD FOR MAKING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-05-21 WO claimed
US-6657038-B1 Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt GENERAL ELECTRIC COMPANY 2003-12-02 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-11898025-B2 Polyethylene with additives for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-02-13 US disclosed
US-11535732-B2 Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-27 US disclosed
US-20210388189-A1 POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-16 US disclosed
US-20210309839-A1 POLYETHYLENE WITH POLYCARBONATE-SILOXANE FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-10-07 US disclosed
EP-3877463-A1 POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE SABIC Global Technologies B.V. (NL) 2021-09-15 EP disclosed
EP-0219302-A2 Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1987-04-22 EP disclosed
US-4520377-A COLOR FORMING LAYER COMO/SED OF ELECTRON DONATING COLORLESS DYE, ELECTRON ACCEPTING COMPOUND, NAPHTHOL UREA AND/OR URETHANE DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1985-05-28 US disclosed
US-4471074-A Heat-sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1984-09-11 US disclosed
US-4471073-A FATTY AMIDES, BISPHENOL COMPOUNDS, DYES FUJI PHOTO FILM CO., LTD. (JP) 1984-09-11 US disclosed
US-4223170-A HEAT DISTORTION RESISTANT POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 1980-09-16 US disclosed
US-4180651-A Polycarbonate composition having resistance to high heat distortion GENERAL ELECTRIC COMPANY (US) 1979-12-25 US disclosed