Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8860952 | 0.82 | ALDH1A1 (0.40) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL4309745 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL866009 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL12936593 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL12277057 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL16707269 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL19464883 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL12803239 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL8861117 | 0.77 | ALDH1A1 (0.36) | ALDH1A1SMYD2CYP3A4 | |
| SCHEMBL8861116 | 0.77 | ALDH1A1 (0.36) | ALDH1A1SMYD2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948511-B1 | CHEMICAL SYNTHESIS OF NUCLEOSIDES ANALOGS AND THEIR INCORPORATION INTO POLYNUCLEOTIDES | SIRNA THERAPEUTICS INC (US) | 2006-10-18 | — | — | EP | disclosed |
| US-6248878-B1 | INCLUDING BASES 2-FLUOROPYRIDINE-3-YL, PYRIDINE-2-ONE-3-YL, PYRIDIN-2-(4-NITROPHENYLETHYL)-ONE-3-YL, 2-BROMOPYRIDINE-5-YL , PYRIDIN-2-ONE-5-YL, 2-AMINOPYRIDINE-5-YL, PYRIDIN-2-(4-NITROPHENYLETHYL)-ONE-5-YL; ANTISENSE/ANTICANCER AGENTS | RIBOZYME PHARMACEUTICALS, INC. | 2001-06-19 | — | — | US | disclosed |