Methylene Chloride

Methylene Chloride

SCHEMBL5953988

ClCCl.ClCCl.O=S(=O)(OS(=O)(=O)C(F)(F)F)C(F)(F)F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylene Chloride SCHEMBL5337444 1.00 CA2 (0.33) CA2CA1CA7CA13
SCHEMBL160 0.87 CA2 (0.41) CA2CA1CA7CA13
SCHEMBL758883 0.87 CA2 (0.41) CA2CA1CA7CA13
SCHEMBL758884 0.87 CA2 (0.41) CA2CA1CA7CA13
SCHEMBL6830251 0.84 CA2 (0.39) CA2CA1CA7CA13
SCHEMBL28351237 0.84 CA2 (0.39) CA2CA1CA7CA13
SCHEMBL6448264 0.84 CA2 (0.39) CA2CA1CA7CA13
SCHEMBL28816823 0.84 CA2 (0.39) CA2CA1CA7CA13
Hydrochloric Acid SCHEMBL29534663 0.84 CA2 (0.39) CA2CA1CA7CA13
SCHEMBL28423969 0.84 CA2 (0.39) CA2CA1CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0948511-B1 CHEMICAL SYNTHESIS OF NUCLEOSIDES ANALOGS AND THEIR INCORPORATION INTO POLYNUCLEOTIDES SIRNA THERAPEUTICS INC (US) 2006-10-18 EP disclosed
US-6506888-B1 Viricides, antitumor and anticarcinogenic agents RIBOZYME PHARMACEUTICALS, INC. 2003-01-14 US disclosed
US-6159951-A 2'-O-amino-containing nucleoside analogs and polynucleotides RIBOZYME PHARMACEUTICALS INC. (US) 2000-12-12 US disclosed
EP-0948511-A2 CHEMICAL SYNTHESIS OF NUCLEOSIDES ANALOGS AND THEIR INCORPORATION INTO POLYNUCLEOTIDES RIBOZYME PHARMACEUTICALS, INC. (US) 1999-10-13 EP disclosed
WO-1998028317-A2 SYNTHESIS OF NUCLEOSIDES AND POLYNUCLEOTIDES RIBOZYME PHARMACEUTICALS, INC. (US) 1998-07-02 WO disclosed