⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466856 | 0.87 | — | — | |
| SCHEMBL3076834 | 0.69 | — | — | |
| SCHEMBL29029892 | 0.69 | ALDH1A1 (0.37) | — | |
| SCHEMBL38753 | 0.63 | — | — | |
| SCHEMBL596764 | 0.62 | — | — | |
| SCHEMBL4070 | 0.62 | — | — | |
| SCHEMBL2608 | 0.61 | — | — | |
| SCHEMBL16145787 | 0.61 | — | — | |
| SCHEMBL57382 | 0.61 | — | — | |
| SCHEMBL8920985 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109503548-B | Butylphthalide derivative and preparation method and application thereof | 江南大学 | 2020-08-04 | — | — | CN | claimed |
| CN-109503548-A | A kind of butylbenzene phthalide derivative and its preparation method and application | 江南大学 | 2019-03-22 | — | — | CN | claimed |
| EP-1469810-A4 | COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF AMYLOID-BETA PEPTIDE-RELATED DISORDERS | UNIV ROCKEFELLER (US) | 2009-01-14 | — | — | EP | claimed |
| US-7332497-B2 | As inhibitors of protein kinases | ABBOTT GMBH & CO KG (DE) | 2008-02-19 | — | — | US | claimed |
| US-20070049594-A1 | Novel compounds and compositions as cathepsin inhibitors | AVENTIS PHARMACEUTICALS INC. (US) | 2007-03-01 | — | — | US | claimed |
| US-20050107310-A1 | Carboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins, analogs, and uses thereof | HOLICK MICHAEL F (US) | 2005-05-19 | — | — | US | claimed |
| EP-1469810-A2 | COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF AMYLOID-BETA PEPTIDE-RELATED DISORDERS | THE ROCKEFELLER UNIVERSITY (US) | 2004-10-27 | — | — | EP | claimed |
| EP-1435352-A2 | 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines | Wyeth Holdings Corporation (US) | 2004-07-07 | — | — | EP | claimed |
| US-20040028673-A1 | Compositions and methods for prevention and treatment of amyloid-beta peptide-related disorders | ROCKEFELLER UNIVERSITY, THE | 2004-02-12 | — | — | US | claimed |
| EP-1383748-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS CATHEPSIN INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-01-28 | — | — | EP | claimed |
| EP-0582788-A1 | 7-(Substituted)-9- (substituted glycyl)-amido)-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0582789-A1 | Novel 7-(substituted)-8-(substituted)-9- (substituted glycyl)amido -6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID COMPANY (US) | 1994-02-16 | — | — | EP | claimed |
| EP-0286089-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES, A COMPOSITION COMPRISING THE SAME, PROCESS FOR PREPARING THE SAME, AND THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS | KANEBO, LTD. (JP) | 1991-11-13 | — | — | EP | claimed |
| US-4971967-A | Quinolinecarboxylic acid derivatives, antibacterial compositions and use | KANEBO LTD (JP) | 1990-11-20 | — | — | US | claimed |
| EP-0387877-A1 | Quinolinecarboxylic acid derivatives and antibacterial agent containing the same | KANEBO LTD. (JP) | 1990-09-19 | — | — | EP | claimed |
| US-4808584-A | Quinolinecarboxylic acid derivatives and antibacterial agent containing the same | KANEBO, LTD. (JP) | 1989-02-28 | — | — | US | claimed |
| EP-0286089-A1 | Quinolinecarboxylic acid derivatives, a composition comprising the same, process for preparing the same, and the use of the same for the manufacture of medicaments | KANEBO, LTD. (JP) | 1988-10-12 | — | — | EP | claimed |
| EP-0047005-B1 | BENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1984-11-14 | — | — | EP | claimed |
| US-4382892-A | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-05-10 | — | — | US | claimed |
| EP-0047005-A1 | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1982-03-10 | — | — | EP | claimed |