Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.86 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dyrene SCHEMBL1903290 | 0.93 | TSHR (1.00) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL6750152 | 0.93 | TSHR (1.00) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL29364667 | 0.93 | TSHR (1.00) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL8166670 | 0.93 | TSHR (1.00) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL13280 | 0.93 | TSHR (1.00) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL133054 | 0.93 | TSHR (1.00) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL14815911 | 0.91 | TSHR (0.89) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL827164 | 0.91 | TSHR (0.96) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL1763275 | 0.91 | TSHR (0.96) | TSHRMAPTKMT2ASMN1; SMN2KDM4E | |
| Dyrene SCHEMBL9734340 | 0.91 | TSHR (0.96) | TSHRMAPTKMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060100317-A1 | Aminoplast molding compounds for products exhibiting an improved flexibility and aminoplast products exhibiting and improved flexibility | AMI - AGROLINZ MELAMINE INTERNATIONAL GMBH (AT) | 2006-05-11 | — | — | US | disclosed |
| EP-0067904-B1 | METHOD OF MODIFYING THE DYE AFFINITY OF CELLULOSE FIBER-CONTAINING STRUCTURE | Toppan Printing Co., Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| US-4392265-A | SULFONATION | TOPPAN PRINTING CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| EP-0067904-A2 | Method of modifying the dye affinity of cellulose fiber-containing structure | Toppan Printing Co., Ltd. (JP) | 1982-12-29 | — | — | EP | disclosed |