Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14286920 | 0.89 | F10 (0.76) | F10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL14286939 | 0.89 | F10 (0.76) | F10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL14286936 | 0.89 | F10 (0.76) | F10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL5956909 | 0.87 | F10 (0.81) | F10POLBMAPT | |
| SCHEMBL5956931 | 0.87 | F10 (0.81) | F10POLBMAPT | |
| SCHEMBL5956923 | 0.85 | F10 (0.57) | F10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL5956933 | 0.83 | F10 (0.58) | F10SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL5956996 | 0.82 | F10 (0.54) | F10 | |
| SCHEMBL3832172 | 0.80 | F10 (0.64) | F10POLB | |
| SCHEMBL8272866 | 0.80 | F10 (0.64) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |