Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.51 |
| ▸ | NAMPT | P43490 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956899 | 1.00 | F10 (0.51) | F10NAMPTTP53NPC1RAB9A | |
| SCHEMBL75773 | 0.89 | F10 (0.63) | F10POLB | |
| SCHEMBL5956996 | 0.88 | F10 (0.54) | F10 | |
| SCHEMBL76300 | 0.80 | F10 (0.67) | F10POLB | |
| SCHEMBL5956860 | 0.80 | F10 (0.61) | F10NAMPTTP53POLB | |
| SCHEMBL5956931 | 0.78 | F10 (0.81) | F10POLB | |
| SCHEMBL5956909 | 0.78 | F10 (0.81) | F10POLB | |
| SCHEMBL5956969 | 0.78 | F10 (0.65) | F10 | |
| SCHEMBL5956979 | 0.78 | F10 (0.54) | F10 | |
| SCHEMBL76504 | 0.76 | F10 (0.67) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |