Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14039721 | 0.90 | F10 (0.55) | F10KLKB1CFDMEN1KMT2A | |
| SCHEMBL5956856 | 0.90 | F10 (0.67) | F10KLKB1 | |
| SCHEMBL5956949 | 0.90 | F10 (0.67) | F10KLKB1 | |
| SCHEMBL5956969 | 0.89 | F10 (0.65) | F10KLKB1CFD | |
| SCHEMBL3830165 | 0.89 | F10 (0.65) | F10KLKB1 | |
| SCHEMBL5956980 | 0.84 | F10 (0.51) | F10KLKB1CFDCYP2C9CYP2C19 | |
| SCHEMBL14039676 | 0.83 | F10 (0.62) | F10KLKB1 | |
| SCHEMBL3834173 | 0.81 | F10 (0.69) | F10KLKB1 | |
| SCHEMBL5957003 | 0.80 | F10 (0.48) | F10KLKB1CFDKMT2ACYP2C9 | |
| SCHEMBL5956996 | 0.80 | F10 (0.54) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |