Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956969 | 0.88 | F10 (0.65) | F10KLKB1CFD | |
| SCHEMBL5956914 | 0.84 | F10 (0.52) | F10KLKB1CFDCYP2C9CYP2C19 | |
| SCHEMBL5957003 | 0.84 | F10 (0.48) | F10KLKB1CFDCYP2C9CYP2C19 | |
| SCHEMBL3832155 | 0.79 | F10 (0.80) | F10KLKB1 | |
| SCHEMBL5956996 | 0.79 | F10 (0.54) | F10 | |
| SCHEMBL5956902 | 0.78 | F10 (0.44) | F10KLKB1CFDCYP2C9CYP2C19 | |
| SCHEMBL5956927 | 0.78 | F10 (0.81) | F10 | |
| SCHEMBL5956946 | 0.78 | F10 (0.67) | F10 | |
| SCHEMBL5956936 | 0.77 | F10 (0.57) | F10KLKB1CFDCYP2C9CYP2C19 | |
| SCHEMBL14039721 | 0.77 | F10 (0.55) | F10KLKB1CFDCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |