Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79092 | 0.87 | F10 (0.62) | F10KLKB1 | |
| SCHEMBL5956969 | 0.87 | F10 (0.65) | F10KLKB1 | |
| SCHEMBL5956996 | 0.85 | F10 (0.54) | F10 | |
| SCHEMBL5956903 | 0.83 | CYP2C9 (0.53) | MEN1KMT2A | |
| SCHEMBL77805 | 0.83 | F10 (0.57) | F10MEN1KMT2A | |
| SCHEMBL4444857 | 0.83 | F10 (0.44) | F10 | |
| SCHEMBL4444861 | 0.83 | F10 (0.44) | F10 | |
| SCHEMBL4447297 | 0.83 | F10 (0.44) | F10 | |
| SCHEMBL5956933 | 0.80 | F10 (0.58) | F10MEN1KMT2AKLKB1 | |
| SCHEMBL5956923 | 0.79 | F10 (0.57) | F10MEN1KMT2AKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |