Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 20/20 | 0.78 |
| ▸ | GRIK2 | Q13002 | 20/20 | 0.78 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958061 | 1.00 | GRIK1 (0.78) | GRIK1GRIK2GRIK3 | |
| SCHEMBL5958288 | 1.00 | GRIK1 (0.78) | GRIK1GRIK2GRIK3 | |
| SCHEMBL594000 | 0.88 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL594001 | 0.88 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL594002 | 0.88 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL593999 | 0.88 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL6014568 | 0.80 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL5958122 | 0.80 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL5957897 | 0.75 | PPARA (0.47) | GRIK1GRIK2GRIK3 | |
| SCHEMBL5958165 | 0.75 | PPARA (0.47) | GRIK1GRIK2GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178496-B2 | Photoreactive regulator of glutamate receptor function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178496-B2 | Photoreactive regulator of glutamate receptor function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-15 | — | — | US | disclosed |
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | ENERGY, UNITED STATE DEPARTMENT OF | 2009-07-16 | — | — | US | disclosed |
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | ENERGY, UNITED STATE DEPARTMENT OF | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181454-A1 | PHOTOREACTIVE REGULATOR OF GLUTAMATE RECEPTOR FUNCTION AND METHODS OF USE THEREOF | GRM2, GRM1, GRM3 | GRIK1 18/4885GRIK2 14/4885GRIK3 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.