Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 20/20 | 1.00 |
| ▸ | GRIK2 | Q13002 | 20/20 | 1.00 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL594001 | 1.00 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL593999 | 1.00 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL594000 | 1.00 | GRIK1 (1.00) | GRIK1GRIK2GRIK3 | |
| SCHEMBL5958288 | 0.88 | GRIK1 (0.78) | GRIK1GRIK2GRIK3 | |
| SCHEMBL5958005 | 0.88 | GRIK1 (0.78) | GRIK1GRIK2GRIK3 | |
| SCHEMBL5958061 | 0.88 | GRIK1 (0.78) | GRIK1GRIK2GRIK3 | |
| SCHEMBL1865552 | 0.85 | GRIK1 (0.73) | GRIK1GRIK2GRIK3 | |
| SCHEMBL3579937 | 0.85 | GRIK1 (0.73) | GRIK1GRIK2GRIK3 | |
| SCHEMBL8087387 | 0.85 | GRIK1 (0.73) | GRIK1GRIK2GRIK3 | |
| SCHEMBL504608 | 0.85 | GRIK1 (0.73) | GRIK1GRIK2GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629911-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150224193-A1 | PHOTOREACTIVE REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-08-13 | — | — | US | disclosed |
| US-9097707-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130137113-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-30 | — | — | US | disclosed |
| US-8309350-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120190094-A1 | Photoreactive Regulator of Protein Function and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-07-26 | — | — | US | disclosed |
| US-8114843-B2 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-14 | — | — | US | disclosed |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-06-07 | — | — | US | disclosed |
| EP-0656345-B1 | Aspartic acid derivatives or homologues thereof and their use in the treatment of neurological diseases | UNIV PASTEUR (FR) | 1999-03-10 | — | — | EP | disclosed |
| US-5739164-A | BLOCK METABOTROPIC GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-5589501-A | TREATMENT OF NEUROLOGICAL DISEASES, ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC AND ANTIEMETIC AGENT | ELI LILLY AND COMPANY (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0656345-A1 | Aspartic acid derivatives or homologues thereof and their use in the treatment of neurological diseases | Université Louis Pasteur (FR) | 1995-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150224193-A1 | PHOTOREACTIVE REGULATOR OF PROTEIN FUNCTION AND METHODS OF USE THEREOF | PPP1R10, PPP6R3, ANKRD52 | GRIK1 3703/4885GRIK2 3511/4885GRIK3 3846/4885 |
| US-20070128662-A1 | Photoreactive regulator of protein function and methods of use thereof | PPP1R10, PPP6R3, ANKRD52 | GRIK1 3703/4885GRIK2 3511/4885GRIK3 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.