SCHEMBL5959010

SCHEMBL5959010

CCCCc1cc(CCCC)c(C(O)C(CC)(CCCC)COP(O)O)c(CCCC)c1

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
S1PR2 O95136 1/20 0.30
S1PR4 O95977 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5959012 0.84 NPC1 (0.33) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL5959007 0.77 S1PR1 (0.31) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL1032615 0.77 ALDH1A1 (0.30)
SCHEMBL496786 0.77 NR5A2 (0.34)
SCHEMBL28108888 0.74 ASAH1 (0.34) NPC1RAB9A
SCHEMBL727871 0.74 NR5A2 (0.30)
SCHEMBL6687742 0.70 NR5A2 (0.31)
SCHEMBL27736510 0.67 NPC1 (0.32) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL2361226 0.66
SCHEMBL27771834 0.65 HPGD (0.43) NPC1HPGDMAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060142446-A1 Process for stabilization of polymer compositions BIO-LAB, INC. 2006-06-29 US disclosed
EP-1585788-A1 IMPROVED PROCESS FOR STABILIZATION OF POLYMER COMPOSITIONS Crompton Corporation (US) 2005-10-19 EP disclosed
WO-2004067622-A1 IMPROVED PROCESS FOR STABILIZATION OF POLYMER COMPOSITIONS CROMPTON CORPORATION (US) 2004-08-12 WO disclosed
US-20040147650-A1 Process for stabilization of polymer compositions GENERAL ELECTRIC COMPANY 2004-07-29 US disclosed