Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5959738 | 0.90 | PPARD (0.51) | PPARDRXRARXRBMAPTPPARG | |
| SCHEMBL5959488 | 0.88 | PPARD (0.66) | PPARDRXRARXRBRXRGPPARA | |
| SCHEMBL5959520 | 0.87 | PPARD (0.53) | PPARDMAPTPPARGPPARALMNA | |
| SCHEMBL5959601 | 0.87 | RXRA (0.53) | PPARDRXRARXRBRXRGMAPT | |
| SCHEMBL5959743 | 0.86 | PPARD (0.53) | PPARDMAPTPPARGPPARALMNA | |
| SCHEMBL5959692 | 0.86 | PPARD (0.53) | PPARDMAPTPPARGPPARALMNA | |
| SCHEMBL5959489 | 0.86 | PPARD (0.50) | PPARDRXRARXRBMAPTPPARG | |
| SCHEMBL5959765 | 0.86 | PPARD (0.50) | PPARDMAPTPPARGPPARALMNA | |
| SCHEMBL5959493 | 0.86 | PPARD (0.50) | PPARDRXRARXRBPPARALMNA | |
| SCHEMBL5959714 | 0.85 | PPARD (0.53) | PPARDRXRARXRBRXRGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091245-B2 | Compounds, their preparation and use | NOVO NOVDISK A/S (DK) | 2006-08-15 | — | — | US | claimed |
| EP-1537076-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR THERAPEUTICAL USE | NOVO NORDISK A/S (DK) | 2005-06-08 | — | — | EP | claimed |
| US-20040143006-A1 | Novel compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC | 2004-07-22 | — | — | US | claimed |
| WO-2004022533-A1 | NOVEL VINYL CARBOXYLIC ACID DERIVATIVES AND THEIR THERAPEUTICAL USE | NOVO NORDISK A/S (DK) | 2004-03-18 | — | — | WO | claimed |
| US-7091245-B2 | Compounds, their preparation and use | NOVO NOVDISK A/S (DK) | 2006-08-15 | — | — | US | disclosed |
| US-20040143006-A1 | Novel compounds, their preparation and use | HIGH POINT PHARMACEUTICALS, LLC | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143006-A1 | Novel compounds, their preparation and use | PPARG, PPARD, PPARA | PPARD 2/4885RXRA 10/4885RXRB 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.