Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 11/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HINT1 | P49773 | 4/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6420722 | 0.94 | TYMP (0.79) | TYMPHPGDHINT1GSK3ARPS6KA3 | |
| SCHEMBL1738400 | 0.90 | TYMP (0.68) | TYMPHPGDHINT1GSK3ARPS6KA3 | |
| SCHEMBL18042134 | 0.90 | TYMP (0.68) | TYMPHPGDHINT1GSK3ARPS6KA3 | |
| SCHEMBL16702978 | 0.90 | TYMP (0.68) | TYMPHPGDHINT1GSK3ARPS6KA3 | |
| SCHEMBL28827051 | 0.89 | TYMP (0.65) | TYMPHPGDHINT1GSK3ARPS6KA3 | |
| SCHEMBL21905181 | 0.89 | TYMP (0.67) | TYMPHPGDHINT1GSK3ARPS6KA3 | |
| SCHEMBL8958859 | 0.89 | TYMP (0.64) | TYMPHPGDHINT1GSK3ARPS6KA3 | |
| SCHEMBL19127268 | 0.88 | TYMP (0.63) | TYMPHPGDHINT1GSK3ARPS6KA3 | |
| SCHEMBL1904550 | 0.87 | TYMP (0.76) | TYMPHINT1GSK3ARPS6KA3MAPK14 | |
| SCHEMBL10904155 | 0.87 | TYMP (0.76) | TYMPHINT1GSK3ARPS6KA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1626086-A2 | Double-stranded nucleic acid molecules with novel chemical compositions capable of modulating gene expression | RIBOZYME PHARMACEUTICALS, INC. (US) | 2006-02-15 | — | — | EP | disclosed |