SCHEMBL5960341

SCHEMBL5960341

Clc1ccc2c(c1Cl)Oc1ccccc1O2

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 13/20 0.70
CYP2A6 P11509 2/20 0.35
ALOX5 P09917 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CYP1A2 P05177 1/20 0.33
FLT1 P17948 1/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
DRD2 P14416 1/20 0.33
GABRA1 P14867 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
DRD1 P21728 1/20 0.33
DRD4 P21917 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1D P25100 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9579677 0.89
SCHEMBL8718012 0.84 AHR (0.72) AHRCYP2A6FLT1
SCHEMBL8712941 0.84 AHR (0.72) AHRCYP2A6FLT1
SCHEMBL8712405 0.84 AHR (0.72) AHRCYP2A6FLT1
SCHEMBL10350071 0.83 AHR (1.00) AHRFLT1
SCHEMBL1806662 0.80 AHR (0.67) AHR
SCHEMBL23529775 0.79 AHR (0.59) AHRALOX5MAOAMAOB
SCHEMBL7064515 0.79 AHR (0.59) AHRCYP2A6ALOX5MAOAMAOB
SCHEMBL5331329 0.77 AHR (0.63) AHRFLT1
SCHEMBL29449476 0.77 AHR (0.63) AHRFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109456756-A A kind of metal-organic framework materials of Zr, preparation method and applications 北京工业大学 2019-03-12 CN claimed
EP-0027745-B1 A PROCESS FOR THE ELECTROCHEMICAL DEGRADATION OF PERSISTENT ORGANIC COMPOUNDS, WITH HARMFUL OR POTENTIALLY HARMFUL PROPERTIES CRECONSULT LIMITED (GB) 1984-08-29 EP claimed
CN-221557971-U Dioxin adsorption equipment 安徽紫朔环境工程技术有限公司 2024-08-20 CN disclosed
CN-104163467-A Ultraviolet synergetic chlorine dioxide water treatment device and method UNIV XIAMEN TECHNOLOGY 2014-11-26 CN disclosed
JP-2006180773-A NEW MICROORGANISM WITH DIOXIN DECOMPOSING POTENTIAL AND METHOD FOR DECOMPOSING DIOXIN KANSAI ELECTRIC POWER CO INC:THE 2006-07-13 JP disclosed
JP-2006180774-A NEW MICROORGANISM WITH DIOXIN DECOMPOSING POTENTIAL AND METHOD FOR DECOMPOSING DIOXIN KANSAI ELECTRIC POWER CO INC:THE 2006-07-13 JP disclosed
US-20040142458-A1 White rot fungi and method for degrading dioxins by using same RYUICHIRO KONDO AND BIO REMEDIATION TECHNOLOGIE, INC. 2004-07-22 US disclosed
US-6653119-B1 Incubating extracellular enzyme and incineration ash in a kirk liquid medium or solid phase; bioremediation; polychlorinated dibenzofuran BIO REMEDIATION TECHNOLOGIE, INC. (JP) 2003-11-25 US disclosed
EP-0770870-B1 Valve and its use GSF FORSCHUNGSZENTRUM UMWELT (DE) 2001-08-01 EP disclosed
EP-1114680-A1 WHITE ROT FUNGUS AND METHOD FOR DEGRADING DIOXINS BY USING THE SAME Wakao Construction Co., Ltd. (JP) 2001-07-11 EP disclosed
EP-0770870-A2 Valve and its use GSF-Forschungszentrum für Umwelt und Gesundheit GmbH (DE) 1997-05-02 EP disclosed
WO-1996024558-A1 METHOD AND APPARATUS FOR THERMAL DECOMPOSITION AND SEPARATION OF COMPONENTS WITHIN AN AQUEOUS STREAM HPR CORPORATION (US) 1996-08-15 WO disclosed
US-5090338-A APPARATUS AND PROCESS FOR TREATING WASTE INCINERATION FLYASH MITSUI ENGINEERING & SHIPBUILDING CO., LTD. (JP) 1992-02-25 US disclosed
EP-0391151-A2 Microbial degradation of multiple halogenated aromatic compounds BAYER AG (DE) 1990-10-10 EP disclosed
US-4238472-A DOUBLE ANTIBODY QUANTITATIVE ANALYSIS; EMULSIFICATION USING AN ETHYLENE OXIDE ALKYLPHENOL ADDUCT UNITED STATES OF AMERICA (US) 1980-12-09 US disclosed
US-4026917-A Method of removing polynuclear aromatic compounds by adsorption with coconut charcoal THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 1977-05-31 US disclosed