Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522608 | 0.87 | PIK3CG (0.70) | PIK3CGMEN1KMT2AMITFRAB9A | |
| SCHEMBL4522979 | 0.82 | PI4KB (0.67) | PIK3CGMEN1KMT2APOLBMAPT | |
| SCHEMBL4520051 | 0.80 | PIK3CG (0.73) | PIK3CGMEN1KMT2AMITFRAB9A | |
| SCHEMBL2835916 | 0.77 | PIK3CG (0.55) | PIK3CGMEN1KMT2AMITFRAB9A | |
| SCHEMBL15940286 | 0.75 | MEN1 (0.51) | PIK3CGMEN1KMT2AMITFRAB9A | |
| SCHEMBL4521807 | 0.74 | PIK3CG (0.73) | PIK3CGMEN1KMT2APOLBLMNA | |
| SCHEMBL4527821 | 0.73 | PIK3CG (0.73) | PIK3CGMEN1KMT2AMITFRAB9A | |
| SCHEMBL4518472 | 0.72 | MEN1 (0.78) | PIK3CGMEN1KMT2AMITFRAB9A | |
| SCHEMBL4520112 | 0.72 | PIK3CG (0.70) | PIK3CGMEN1KMT2AMITFRAB9A | |
| SCHEMBL4520044 | 0.71 | MEN1 (0.71) | PIK3CGMEN1KMT2AMITFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709019-A2 | THIAZOLE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005068444-A2 | THIAZOLE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-07-28 | — | — | WO | disclosed |