Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.53 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600476 | 0.86 | TRPV1 (0.55) | TRPV1METAP2KIF11 | |
| SCHEMBL5960381 | 0.82 | TRPV1 (0.51) | TRPV1METAP2 | |
| SCHEMBL4974349 | 0.80 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL4357729 | 0.80 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL4973901 | 0.77 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL4360226 | 0.77 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL5479649 | 0.76 | TRPV1 (0.71) | TRPV1 | |
| SCHEMBL4908519 | 0.76 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL4357351 | 0.76 | TRPV1 (0.67) | TRPV1 | |
| Hydrochloric Acid SCHEMBL6364830 | 0.75 | TRPV1 (0.67) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732560-A1 | SUBSTITUTED CINNOLIN-4-YLAMINES | NEUROGEN CORPORATION (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005099710-A1 | SUBSTITUTED CINNOLIN-4-YLAMINES | NEUROGEN CORPORATION (US) | 2005-10-27 | — | — | WO | disclosed |