Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27600560 | 0.85 | TRPV1 (0.51) | TRPV1METAP2 | |
| SCHEMBL5960372 | 0.82 | TRPV1 (0.53) | TRPV1METAP2 | |
| SCHEMBL27659490 | 0.77 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL4911389 | 0.75 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL4908258 | 0.75 | TRPV1 (0.67) | TRPV1 | |
| SCHEMBL5469359 | 0.74 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL4973479 | 0.74 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL7230262 | 0.72 | MAP4K4 (0.50) | TRPV1 | |
| SCHEMBL904619 | 0.72 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL5918308 | 0.72 | TRPV1 (0.47) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732560-A1 | SUBSTITUTED CINNOLIN-4-YLAMINES | NEUROGEN CORPORATION (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005099710-A1 | SUBSTITUTED CINNOLIN-4-YLAMINES | NEUROGEN CORPORATION (US) | 2005-10-27 | — | — | WO | disclosed |