Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.58 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.56 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960459 | 1.00 | PTPN1 (0.58) | PTPN1HNF4ASLC5A1SLC5A2AHR | |
| SCHEMBL19420358 | 0.86 | PTGS1 (0.58) | PTPN1PTPN6TTRCA12CA1 | |
| SCHEMBL25522549 | 0.85 | AHR (0.56) | PTPN1HNF4ASLC5A1SLC5A2AHR | |
| SCHEMBL19420484 | 0.82 | LCK (0.65) | PTPN1HNF4APTPN6TTRCA12 | |
| SCHEMBL6229522 | 0.80 | SLC5A1 (0.61) | PTPN1HNF4ASLC5A1SLC5A2TTR | |
| SCHEMBL5960451 | 0.80 | CA12 (0.56) | PTPN1SLC5A1SLC5A2AHRTTR | |
| SCHEMBL6229519 | 0.80 | SLC5A1 (0.61) | PTPN1HNF4ASLC5A1SLC5A2TTR | |
| SCHEMBL30358577 | 0.80 | SLC5A1 (0.61) | PTPN1HNF4ASLC5A1SLC5A2TTR | |
| SCHEMBL5960447 | 0.80 | CA12 (0.56) | PTPN1SLC5A1SLC5A2AHRTTR | |
| SCHEMBL10597010 | 0.79 | PTPN1 (0.71) | PTPN1HNF4AAHRPTPN6TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | claimed |
| US-11253455-B2 | Carboxylated polyphenol derivatives and their cosmetic use | L'ORÉAL (FR) | 2022-02-22 | — | — | US | disclosed |
| US-11058619-B2 | Carboxylated polyphenol derivatives and their cosmetic use | L'ORÉAL (FR) | 2021-07-13 | — | — | US | disclosed |
| US-20200197275-A1 | CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE | L'OREAL (FR) | 2020-06-25 | — | — | US | disclosed |
| US-20190151215-A1 | CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE | L'ORÉAL (FR) | 2019-05-23 | — | — | US | disclosed |
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151215-A1 | CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE | H1-0, GLA, NQO1 | PTPN1 4781/4885HNF4A 3616/4885SLC5A1 4396/4885 |
| US-20200197275-A1 | CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE | H1-0, GLA, NQO1 | PTPN1 4754/4885HNF4A 3303/4885SLC5A1 4088/4885 |
| US-11253455-B2 | Carboxylated polyphenol derivatives and their cosmetic use | H1-0, GLA, NQO1 | PTPN1 4781/4885HNF4A 3616/4885SLC5A1 4396/4885 |
| US-11058619-B2 | Carboxylated polyphenol derivatives and their cosmetic use | H1-0, GLA, NQO1 | PTPN1 4754/4885HNF4A 3303/4885SLC5A1 4088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.