Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.58 |
| ▸ | HNF4A | P41235 | 1/20 | 0.58 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.56 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960458 | 1.00 | PTPN1 (0.58) | PTPN1HNF4ASLC5A1SLC5A2AHR | |
| SCHEMBL19420358 | 0.86 | PTGS1 (0.58) | PTPN1PTPN6TTRCA12CA1 | |
| SCHEMBL25522549 | 0.85 | AHR (0.56) | PTPN1HNF4ASLC5A1SLC5A2AHR | |
| SCHEMBL19420484 | 0.82 | LCK (0.65) | PTPN1HNF4APTPN6TTRCA12 | |
| SCHEMBL6229522 | 0.80 | SLC5A1 (0.61) | PTPN1HNF4ASLC5A1SLC5A2TTR | |
| SCHEMBL5960451 | 0.80 | CA12 (0.56) | PTPN1SLC5A1SLC5A2AHRTTR | |
| SCHEMBL6229519 | 0.80 | SLC5A1 (0.61) | PTPN1HNF4ASLC5A1SLC5A2TTR | |
| SCHEMBL30358577 | 0.80 | SLC5A1 (0.61) | PTPN1HNF4ASLC5A1SLC5A2TTR | |
| SCHEMBL5960447 | 0.80 | CA12 (0.56) | PTPN1SLC5A1SLC5A2AHRTTR | |
| SCHEMBL10597010 | 0.79 | PTPN1 (0.71) | PTPN1HNF4AAHRPTPN6TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | claimed |
| WO-2006004722-A2 | COMPOSITIONS AND METHODS FOR SELECTIVELY ACTIVATING HUMAN SIRTUINS | BIOMOL RESEARCH LABORATORIES, INC. (US) | 2006-01-12 | — | — | WO | disclosed |