Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.70 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.70 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.70 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.70 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.70 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | GJB2 | P29033 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 6/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31491488 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL15338590 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL1957129 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13204994 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL13591468 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL12896361 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL5961352 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL3752664 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL6872203 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL30928985 | 1.00 | SSTR1 (0.70) | SSTR1SSTR2SSTR4SSTR3SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838508-B2 | 4′-thio-L-xyloy furanosyl nucleosides, precursors thereof, preparation and use thereof | SOUTHERN RESEARCH INSTITUTE (US) | 2010-11-23 | — | — | US | disclosed |
| US-20070112004-A1 | 4'-THIO-L-XYLOY FURANOSYL NUCLEOSIDES, PRECURSORS THEREOF, PREPARATION AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2007-05-17 | — | — | US | disclosed |
| US-7148223-B2 | Compounds for use as viricides, anticarcinogenic agents and inhibit DNA replication | SOUTHERN RESEARCH INSTITUTE (US) | 2006-12-12 | — | — | US | disclosed |
| US-6914061-B2 | 4′-thio-L-xylofuranosyl nucleosides, precursors thereof, preparation and use thereof | SOUTHERN RESEARCH INSTITUTE (US) | 2005-07-05 | — | — | US | disclosed |
| US-20050130969-A1 | 4'-Thio-L-xyloy furanosyl nucleosides, precursors thereof, preparation and use thereof | SOUTHERN RESEARCH INSTITUTE (US) | 2005-06-16 | — | — | US | disclosed |
| US-20030144235-A1 | Anticarcinogenic agents for treating cancer, a viricides for viral diseases, inhibit DNA replication | SOUTHERN RESEARCH INSTITUTE | 2003-07-31 | — | — | US | disclosed |
| WO-2001066118-A1 | 4'-THIO-L-XYLO FURANOSYL NUCLEOSIDES, PRECURSORS THEREOF, PREPARATION AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2001-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144235-A1 | Anticarcinogenic agents for treating cancer, a viricides for viral diseases, inhibit DNA replication | POLL, PCNA, YWHAZ | SSTR1 4424/4885SSTR2 4766/4885SSTR4 4663/4885 |
| US-20070112004-A1 | 4'-THIO-L-XYLOY FURANOSYL NUCLEOSIDES, PRECURSORS THEREOF, PREPARATION AND USE THEREOF | POLL, PNP, UNG | SSTR1 4227/4885SSTR2 4691/4885SSTR4 4055/4885 |
| US-20050130969-A1 | 4'-Thio-L-xyloy furanosyl nucleosides, precursors thereof, preparation and use thereof | POLL, PNP, UNG | SSTR1 4227/4885SSTR2 4691/4885SSTR4 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.