Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3321971 | 0.76 | TDP1 (0.39) | TDP1EYA2APPACELMNA | |
| SCHEMBL162905 | 0.76 | TDP1 (0.39) | TDP1EYA2APPACELMNA | |
| Hydrochloric Acid SCHEMBL5560964 | 0.74 | TDP1 (0.38) | TDP1EYA2APPACELMNA | |
| SCHEMBL22061 | 0.74 | TDP1 (0.47) | TDP1EYA2APPACELMNA | |
| SCHEMBL9357262 | 0.72 | TDP1 (0.41) | TDP1EYA2APPACELMNA | |
| SCHEMBL31079566 | 0.72 | TSHR (0.37) | TSHRAKR1B10AKR1A1AKR1B1 | |
| SCHEMBL24709971 | 0.72 | TDP1 (0.36) | TDP1EYA2APPACELMNA | |
| SCHEMBL18362436 | 0.72 | TDP1 (0.36) | TDP1EYA2APPACELMNA | |
| Trifluoroacetic Acid SCHEMBL18953992 | 0.72 | TDP1 (0.36) | TDP1EYA2APPACELMNA | |
| SCHEMBL18229249 | 0.71 | TDP1 (0.45) | TDP1EYA2APPACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203438-A | Condensed imidazole compound with indole amine 2,3-dioxygenase inhibitory activity | 深圳微芯生物科技股份有限公司 | 2018-06-26 | — | — | CN | disclosed |
| US-6992086-B2 | Antagonists of MCP-1 function and methods of use thereof | TELIK, INC. (US) | 2006-01-31 | — | — | US | disclosed |