Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | EYA2 | O00167 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13303095 | 0.74 | — | — | |
| SCHEMBL13596346 | 0.74 | ALDH1A1 (0.33) | TDP1LMNA | |
| SCHEMBL5961426 | 0.72 | TDP1 (0.38) | TDP1EYA2APPACELMNA | |
| SCHEMBL816963 | 0.72 | EGLN1 (0.47) | LMNAPMP22KDM4ETSHRALKBH5 | |
| SCHEMBL3657584 | 0.71 | TDP1 (0.41) | TDP1EYA2APPACELMNA | |
| SCHEMBL13303091 | 0.69 | TSHR (0.42) | LMNAKDM4ETSHRMLYCDHSD17B10 | |
| SCHEMBL3803673 | 0.69 | TDP1 (0.39) | TDP1EYA2APPACELMNA | |
| SCHEMBL9748731 | 0.69 | ADRA1A (0.43) | TDP1EYA2APPACELMNA | |
| SCHEMBL10909276 | 0.69 | ADRA1A (0.43) | TDP1EYA2APPACELMNA | |
| SCHEMBL2323615 | 0.67 | TDP1 (0.50) | TDP1EYA2APPACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152081-A1 | Fluorosurfactants | MERCK PATENT GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20090320718-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| US-20090320718-A1 | FLUOROSURFACTANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-0548155-B1 | PROCESS FOR PREPARING TERTIARY PERFLUOROAMINES | MINNESOTA MINING & MFG (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0548155-A1 | PROCESS FOR PREPARING TERTIARY PERFLUOROAMINES. | MINNESOTA MINING & MFG (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5108556-A | Electrochemically fluorinating a tertiary thioamide precursor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| WO-1992005142-A1 | PROCESS FOR PREPARING TERTIARY PERFLUOROAMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152081-A1 | Fluorosurfactants | CBR3, FPR3, NOX3 | TDP1 4767/4885EYA2 3389/4885APP 4404/4885 |
| US-20090320718-A1 | FLUOROSURFACTANTS | FPR3, Q6ZSR9, SGMS2 | TDP1 2928/4885EYA2 1211/4885APP 4314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.