Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | BLK | P51451 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961482 | 0.82 | CCR2 (0.51) | CCR2CCR5KDRABL1LCK | |
| SCHEMBL6904399 | 0.81 | CCR2 (0.49) | CCR2CCR5KDRABL1LCK | |
| SCHEMBL5961552 | 0.75 | CCR2 (0.47) | CCR2CCR5KDRABL1LCK | |
| SCHEMBL5961532 | 0.74 | CCR2 (0.69) | CCR2CCR5KDRABL1LCK | |
| SCHEMBL5961553 | 0.74 | CCR2 (0.45) | CCR2CCR5KDRABL1LCK | |
| SCHEMBL5961555 | 0.74 | CCR2 (0.51) | CCR2CCR5KDRABL1LCK | |
| SCHEMBL5961444 | 0.74 | CCR2 (0.47) | CCR2CCR5KDRABL1LCK | |
| Hydrochloric Acid SCHEMBL5961481 | 0.72 | CCR2 (0.50) | CCR2CCR5KDRABL1LCK | |
| SCHEMBL5961472 | 0.72 | CCR2 (0.63) | CCR2CCR5KDRABL1LCK | |
| SCHEMBL5961588 | 0.72 | CCR2 (0.47) | CCR2CCR5KDRABL1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6992086-B2 | Antagonists of MCP-1 function and methods of use thereof | TELIK, INC. (US) | 2006-01-31 | — | — | US | disclosed |