Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824686 | 0.87 | PARP1 (0.86) | PARP1 | |
| SCHEMBL12955358 | 0.80 | PARP1 (0.72) | PARP1 | |
| SCHEMBL1689414 | 0.78 | PARP1 (1.00) | PARP1 | |
| SCHEMBL1689488 | 0.78 | PARP1 (1.00) | PARP1 | |
| SCHEMBL30415984 | 0.78 | PARP1 (1.00) | PARP1 | |
| SCHEMBL30416453 | 0.77 | PARP1 (0.73) | PARP1 | |
| SCHEMBL77913 | 0.77 | PARP1 (0.73) | PARP1 | |
| SCHEMBL19569946 | 0.77 | PARP1 (0.93) | PARP1 | |
| SCHEMBL15218259 | 0.76 | PARP1 (0.69) | PARP1 | |
| SCHEMBL77391 | 0.76 | PARP1 (0.75) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633724-A1 | PHTHALAZINONE DERIVATIVES | Kudos Pharmaceuticals Limited (GB) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004080976-A1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARMACEUTICALS LIMITED (GB) | 2004-09-23 | — | — | WO | disclosed |