Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
| ▸ | DCUN1D2 | Q6PH85 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1131262 | 0.99 | CSNK2A1 (0.50) | CSNK2A1TAAR1SGK1DPP4BACE1 | |
| SCHEMBL1774163 | 0.87 | FOLH1 (0.37) | CSNK2A1BACE1FOLH1 | |
| SCHEMBL8674236 | 0.86 | FOLH1 (0.33) | CSNK2A1BACE1FOLH1SMARCA2SMARCA4 | |
| SCHEMBL27466258 | 0.86 | CSNK2A1 (0.36) | CSNK2A1BACE1FOLH1LMNADCUN1D2 | |
| Benzylamine SCHEMBL27675029 | 0.85 | DPP4 (0.43) | CSNK2A1TAAR1SGK1DPP4AKT2 | |
| SCHEMBL1132111 | 0.84 | TAAR1 (0.43) | CSNK2A1TAAR1SGK1DPP4AKT2 | |
| SCHEMBL27452763 | 0.83 | TDP1 (0.36) | CSNK2A1BACE1FOLH1DCUN1D2DCUN1D1 | |
| Hydrochloric Acid SCHEMBL1131050 | 0.82 | AKT2 (0.42) | CSNK2A1TAAR1SGK1DPP4AKT2 | |
| SCHEMBL27259186 | 0.82 | CSNK2A1 (0.33) | CSNK2A1FOLH1 | |
| SCHEMBL594529 | 0.79 | MAPT (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753746-B8 | NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | ROTTAPHARM SPA (IT) | 2012-02-15 | — | — | EP | disclosed |
| EP-1753746-A2 | NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | ROTTAPHARM S.P.A. (IT) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005105789-A2 | NOVEL PYRROLE DERIVATIVES WITH ANGIOTENSIN II ANTAGONIST ACTIVITY | ROTTAPHARM S.P.A. (IT) | 2005-11-10 | — | — | WO | disclosed |