SCHEMBL5962488

SCHEMBL5962488

CCOC(=O)N1c2ccccc2Cc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.61
KMT2A Q03164 5/20 0.52
MEN1 O00255 3/20 0.52
LMNA P02545 1/20 0.52
NOTUM Q6P988 2/20 0.51
KDM4E B2RXH2 1/20 0.50
MAPT P10636 2/20 0.48
TUBB4A P04350 1/20 0.48
TUBB P07437 1/20 0.48
TUBA3C P0DPH7 1/20 0.48
TUBA1B P68363 1/20 0.48
TUBA4A P68366 1/20 0.48
TUBB4B P68371 1/20 0.48
TUBB3 Q13509 1/20 0.48
TUBB2A Q13885 1/20 0.48
TUBB8 Q3ZCM7 1/20 0.48
TUBA3E Q6PEY2 1/20 0.48
TUBA1A Q71U36 1/20 0.48
TUBA1C Q9BQE3 1/20 0.48
TUBB6 Q9BUF5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8436386 0.90 KMT2A (0.62) BCHEKMT2AMEN1LMNANOTUM
SCHEMBL11980498 0.89 NOTUM (0.64) BCHEKMT2AMEN1LMNANOTUM
SCHEMBL9312975 0.87 BCHE (0.58) BCHEKMT2AMEN1LMNANOTUM
SCHEMBL2698571 0.85 BCHE (0.73) BCHELMNAMAPTGAASMN1; SMN2
SCHEMBL2322460 0.85 BCHE (0.73) BCHELMNAMAPTGAASMN1; SMN2
SCHEMBL19139141 0.79 BCHE (0.65) BCHEKMT2AMEN1LMNAKDM4E
SCHEMBL5530211 0.79 BCHE (0.65) BCHELMNANOTUMGAASMN1; SMN2
SCHEMBL29479856 0.78 BCHE (0.62) BCHEKMT2AMEN1NOTUMKDM4E
SCHEMBL27472465 0.78 P2RX4 (0.62) BCHEKMT2AMEN1NOTUMKDM4E
SCHEMBL11412073 0.77 P2RX4 (0.71) BCHELMNASMN1; SMN2P2RX4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0028337-B1 PROCESS FOR PREPARING MIXTURES OF DIPHENYLMETHANE DIISOCYANATES AND POLYPHENYL-POLYMETHYLENE POLYISOCYANATES BASF Aktiengesellschaft (DE) 1985-02-13 EP claimed
US-7022871-B2 Process for the synthesis of polycarbamates HUNTSMAN INTERNATIONAL LLC (US) 2006-04-04 US disclosed
EP-1242368-B1 PROCESS FOR THE SYNTHESIS OF POLYCARBAMATES HUNTSMAN INT LLC (US) 2004-09-15 EP disclosed
US-20030135009-A1 Process for the synthesis of polycarbamates HUNTSMAN INTERNATIONAL LLC 2003-07-17 US disclosed
EP-1242368-A2 PROCESS FOR THE SYNTHESIS OF POLYCARBAMATES HUNTSMAN INTERNATIONAL LLC (US) 2002-09-25 EP disclosed
EP-0881213-B1 Process for the synthesis of aromatic urethanes MINI RICERCA SCIENT TECNOLOG (IT) 2001-09-19 EP disclosed
WO-2001047871-A2 PROCESS FOR THE SYNTHESIS OF POLYCARBAMATES HUNTSMAN INTERNATIONAL LLC (US) 2001-07-05 WO disclosed
US-6034265-A REACTING A CARBONATE WITH AROMATIC AMINE MINISTERO DELL'UNIVERSITA E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 2000-03-07 US disclosed
EP-0881213-A2 Process for the synthesis of aromatic urethanes MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) 1998-12-02 EP disclosed
EP-0028338-B2 PROCESS FOR PREPARING AROMATIC DI- AND/OR POLYISOCYANATES BASF Aktiengesellschaft (DE) 1986-02-26 EP disclosed
EP-0028337-B1 PROCESS FOR PREPARING MIXTURES OF DIPHENYLMETHANE DIISOCYANATES AND POLYPHENYL-POLYMETHYLENE POLYISOCYANATES BASF Aktiengesellschaft (DE) 1985-02-13 EP disclosed
EP-0028338-B1 PROCESS FOR PREPARING AROMATIC DI- AND/OR POLYISOCYANATES BASF Aktiengesellschaft (DE) 1984-01-18 EP disclosed
US-4349484-A Process for the manufacture of mixtures of diphenylmethane diisocyanates and polyphenyl polymethylene polyisocyanates BASF AKTIENGESELLSCHAFT (DE) 1982-09-14 US disclosed
EP-0028338-A2 Process for preparing aromatic di- and/or polyisocyanates BASF Aktiengesellschaft (DE) 1981-05-13 EP disclosed
EP-0028337-A2 Process for preparing mixtures of diphenylmethane diisocyanates and polyphenyl-polymethylene polyisocyanates BASF Aktiengesellschaft (DE) 1981-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030135009-A1 Process for the synthesis of polycarbamates ODC1, UROD, PUF60 BCHE 3306/4885KMT2A 127/4885MEN1 2162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.